"Spontaneous epileptic rats show changes in sleep architecture and hypothalamic pathology." Epilepsia 46.6 (2005): 934-938.ĭatta, Subimal, and Robert Ross MacLean. "Investigation of the sleep electrocorticogram of the common marmoset ( Callithrix jacchus) using radiotelemetry." Clinical Neurophysiology, 112.12 (2001): 2265-2273.īastlund, Jesper F., et al. "Video-electroencephalography in conscious non human primate using radiotelemetry and computerized analysis: refinement of a safety pharmacology model." Journal of Pharmacological and Toxicological Methods, 60.1 (2009): 88-93.Ĭrofts, H. "Photoperiod alters duration and intensity of non-rapid eye movement sleep following immune challenge in Siberian hamsters (Phodopus sungorus)." Chronobiology International, 29.6 (2012): 683-692.Īuthier, S., et al. Researchers can use restrained or unrestrained techniques, depending on their model, to acquire a variety of respiratory endpoints in their sleep studies.Īshley, Noah T., et al. In addition, many neurological disorders, spinal cord injuries, traumatic brain injuries, and movement disorders have been shown to cause respiratory complications during sleep. OSA has been linked to disorders of the cardiovascular, metabolic, and endocrine systems. One commonly studied disorder is obstructive sleep apnea (OSA) which causes a decrease in muscle tone in the upper airway, leading to reduced oxygenation during sleep. Researchers study basic respiratory mechanisms of sleep, as well as sleeping related disorders, to gain a better understanding of respiratory function during different sleep stages. The exception to this is during REM sleep when shallow, irregular, and increased breathing patterns occur. During a majority of sleep, respiration is regular with noted decreases in rate and minute volume when compared to wakefulness.
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